For these engaged in opioid agonist remedy (OAT), cannabis might be an efficient technique to cut back fentanyl publicity.

That’s the takeaway from a new study revealed this month within the journal Drug and Alcohol Dependence. 

Drawing information from “two community-recruited potential cohorts of people that use medication in Vancouver, Canada,” the researchers from the College of British Columbia, Heart of Substance Use stated they studied “the connection between hashish use and up to date fentanyl publicity” amongst OAT contributors between the years 2016 and 2018.

OAT is “an efficient therapy for habit to opioid medication equivalent to heroin, oxycodone, hydromorphone (Dilaudid), fentanyl and Percocet,” according to the Canadian research hospital Centre for Addiction and Mental Health, that “includes taking the opioid agonists methadone (Methadose) or buprenorphine (Suboxone)” as a part of an effort to forestall withdrawal and cut back cravings.

The analysis revealed in Drug and Alcohol Dependence was primarily based on “819 contributors on OAT who contributed 1989 observations over the examine interval.” Based on the researchers, fentanyl publicity was “frequent.”

“On the baseline interview, fentanyl was detected in a majority of contributors,” the researchers wrote, saying that it was detected in 53 % of the contributors, however that general “hashish use was independently related to lowered probability of being not too long ago uncovered to fentanyl.”

“[W]e discovered that amongst greater than 800 contributors on OAT in Vancouver, Canada, use of hashish was longitudinally related to a considerably decrease threat of being uncovered to fentanyl. Given the magnitude of the overdose disaster within the U.S. and Canada and the substantial contributions of fentanyl to the burden of overdose morbidity and mortality, findings from this examine assist the experimental analysis of cannabinoids as a possible adjunct remedy to OAT to enhance scientific outcomes, significantly to scale back the danger of relapse to illicit opioid use (i.e., fentanyl) and related threat of overdose and dying,” the researchers wrote, as quoted by NORML.

The Function of Hashish In The Opioid Disaster

The examine is the newest in a rising physique of analysis to recommend that hashish could also be an efficient weapon within the struggle in opposition to the opioid disaster. And because the researchers within the aforementioned examine famous, the “ongoing opioid overdose disaster is pushed largely by publicity to illicitly-manufactured fentanyl.”

In July, a study revealed within the journal Systematic Opinions discovered “a a lot larger discount in opioid dosage, lowered emergency room visits, and hospital admissions for persistent non-cancer ache by MC [medical cannabis] customers, in comparison with folks with no extra use of MC.” 

“There was 64 to 75 % discount in opioid dosage for MC customers and full stoppage of opioid use for persistent non-cancer ache by 32 to 59 % of MC customers, when in comparison with sufferers with out extra use of MC,” the researchers of that examine wrote.

And in June, research revealed within the Journal of Psychopharmacology discovered “behavioral financial proof that hashish entry might modestly cut back demand for opioids in individuals who’ve ache.”

“Adults reporting present use of opioids for ache administration and previous 30-day hashish publicity…accomplished two hypothetical buy duties by which solely grams of hashish or items of contributors’ index opioids have been obtainable for buy, and two hypothetical duties by which each have been concurrently obtainable and the value of 1 drug elevated whereas the opposite was saved fixed,” the researchers wrote.